(2R)-2-(2-chlorophenyl)-2-(methylamino)-cyclohexanone, monohydrochloride
\nThe receptor for NMDA is a glutamate-gated ion channel that has key roles in synaptic plasticity, memory acquisition, hyperalgesia, and allodynia.{5566,14639,21239} Ketamine (Item No. 11630) is an NMDA receptor channel blocker (Ki = 1.2-2.5 μM, IC50 = 3.2-6.1 μM).{25284,25283} (R)-Ketamine is about 4 times less potent as an analgesic than the S-enantiomer.{21239} It is a dissociative anesthetic that has analgesic properties at subanesthetic doses.{21239} Ketamine and its analog methoxetamine (Item No. 11139) are abused recreationally.{21236,21240,21237,21241} Ketamine is regulated as a Schedule III compound in the United States. This product is intended for forensic and research purposes.
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